学习经历
2016.10-2020.12，奈梅亨大学拉德堡德分子生命科学研究所，计算生物学博士
2013.09-2016.03，开云官方在线登陆入口，生物学硕士
2008.09-2012.06，湖南师范大学生命科学学院，生物技术学士
工作经历
2026.01至今，开云官方在线登陆入口，特别研究员（博士生导师）
2023.01-2025.12，罗氏制药人类生物学研究所，博士后
2022.05-2022.12，诺华制药巴塞尔分子与临床眼科研究所，博士后
2021.01-2022.05，诺华制药巴塞尔分子与临床眼科研究所，研究助理
人才奖项
2026年，上海交通大学“思源青年学者”
2025年，国家优秀青年科学基金（海外）
2025年，上海市海外高层次人才计划
1. 正常与肿瘤等重大疾病相关类器官模型的构建及其在疾病机制研究与功能验证中的应用；
2. 整合（空间）单细胞组学等多组学大数据，挖掘多类型疾病的关键调控网络与潜在治疗靶点，并指导疾病类器官建模与验证；
3. 支撑多组学数据解析的生物信息学算法、计算方法与分析工具开发。
*：第一作者，#：通讯作者
1. Akkerman, N.*, Xu, Q.*, ..., Camp, JG.#, Beumer, J.# (2026). An organoid model of the human adrenal cortex identifies drivers of steroidogenesis and zonation. Cell Press Blue. Highlighted in Cell Stem Cell.
2. Xu, Q.*,#, Halle, L.*, ..., Treutlein, B.#, Theis, F.#, Camp, JG.# (2025). An integrated transcriptomic cell atlas of human endoderm-derived organoids. Nature Genetics. Highlighted in Nature.
3. Xu, Q.*, Okuda, R.*, Gjeta, B.*, ..., Treutlein B.#, Camp, JG.# (2025). Integrated cell atlas and tumoroids chart pancreatic cancer therapeutic targets. bioRxiv.
4. Okuda, R.*, Harmel, C.*, Xu, Q., ..., Camp, JG.# (2025). An integrated platform for high-throughput phenospace learning of 3D multilineage organoid systems. bioRxiv.
5. Muller, A., ... Xu, Q., ..., Roska, B.#, György, B.# (2025). High-efficiency base editing for Stargardt disease in mice, non-human primates, and human retina tissue. Nature Medicine.
6. Mitrofanova, O., Nikolaev, M., Xu, Q., ..., Camp, JG., Lutolf, M. P.# (2024). Bioengineered human colon organoids with in vivo-like complexity and function. Cell Stem Cell. Highlighted in Cell Stem Cell.
7. Xu, Q., ..., Zhou, H.#, van Heeringen, S.J.# (2021). ANANSE: An enhancer network-based computational approach for predicting key transcription factors in cell fate determination. Nucleic Acids Research.
8. Soares, E.*, Xu, Q.*, Li, Q.*, ..., Tang, F.#, Zhou, H.# (2019). Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndrome. PNAS.
9. Zhai., Y., Xu, Q., ..., Wu, Q.# (2016). Characterization of a cluster of CTCF-binding sites in a protocadherin regulatory region. Hereditas.
10. Guo, Y.*, Xu, Q.*, ..., Maniatis, T.#, Wu, Q.# (2015). CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. Highlighted in Cell and Nature Reviews Molecular Cell Biology, Cited >1100 times.
11. Li, J., Shou, J., ..., Xu, Q., Wu, Q.# (2015). Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9. Journal of Molecular Cell Biology.
12. Jia, Z., ..., Xu, Q., ..., Wu, Q.# (2014). Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity. Molecular and Cellular Biology.
实验室刚刚建立，期待有志于前沿生物医学研究的青年学者（包括博士后、博士生、硕士生、本科生、实习生等）加入，共同为推动人类健康事业贡献力量！
